Day: April 12, 2013

Australian Museum celebrates blockbuster exhibition by announcing the The Week of Alexander – 22 to 26 April Calling all named Alex & residents of Alexandria

Australian Museums blockbuster exhibition Alexander the Great: 2000 Years of treasures must close its doors on Sunday 28 April after setting attendance records for the museum over summer.

As a final celebration before these treasures are packed for transport back to the State Hermitage in St Petersburg, the Australian Museum announce The Week of Alexander.

Between Monday 22 and Friday 26 April, anyone who has Alex in their first or surname will gain entry at a special price. (proof of identity required)

And as Alexander the Great founded 20 cities that bore his name, the Museum has extended this offer to all residents of Alexandria. (proof of address required)

I urge people to take the opportunity to see these treasures for 28 April as they will not travel to Australia again in our lifetime, says Frank Howarth, Director of the Australian Museum. And I urge all Alexes to come along and discover the legacy of their famous historic namesake.

The Week of Alexander offer
to purchase your discounted tickets mention the promotional word ALEX
Adult $18 (normally $24) saving of $6 or a 25% discount
Family $50 (2 adults & 2 children – normally $60) saving of $10 or 16% discount

Alexander the Great: 2000 years of treasures
Collection from the State Hermitage, St Petersburg, Russia
Exclusive in Australia to the Australian Museum in Sydney
http://www.alexandersydney.com.au

Tickets available at the museum, but to avoid the queues pre-purchase tickets
at http://www.ticketmaster.com.au or by calling 136 100

Scientists develop simple blood test to track tumour evolution in cancer patients

Source CancerResearch.uk

Cancer Research UK Press Release

Cancer Research UK scientists have developed a new way of looking at how tumours evolve in real-time and develop drug resistance by tracking changes in the patients’ blood, described in a study1 published in Nature.

Scientists at the Cancer Research UK Cambridge Institute at the University of Cambridge2 used traces of tumour DNA, known as circulating tumour DNA (ctDNA) found in cancer patients’ blood to follow the progress of the disease as it changed over time and developed resistance to chemotherapy treatments.

They followed six patients with advanced breast, ovarian and lung cancers and took blood samples, which contained small amounts of tumour ctDNA, over one to two years.

By looking for changes in the tumour ctDNA before and after each course of treatment, they were able to identify which changes in the tumour’s DNA were linked to drug resistance following each treatment session.

Using this new method they were able to identify several changes linked to drug-resistance in response to chemotherapy drugs such as paclitaxel (taxol) which is used to treat ovarian, breast and lung cancers, tamoxifen which is used to treat oestrogen-positive breast cancers and transtuzumab (Herceptin) which is used to treat HER2 positive breast cancers.

And they hope this will help shed new light on how cancer tumours develop resistance to some of our most effective chemotherapy drugs as well as providing an alternative to current methods of collecting tumour DNA – by taking a sample direct from the tumour – a much more difficult and invasive procedure.

Dr Nitzan Rosenfeld, Cancer Research UK funded scientist and one of the study authors, said: “Tumours are constantly changing and evolving which helps them develop a resistance to many of the drugs we currently give patients to treat their disease.

“We’ve shown that a very simple blood test can be used to collect enough tumour DNA to suggest to us what parts of the cancer’s genetic code is changing and creating tumour resistance to chemotherapy or biologically-targeted therapies.

“We hope that our discoveries can pave the way to helping us understand how cancers develop drug resistance as well as identifying new potential targets for future cancer drugs.”

Kate Law, director of clinical research at Cancer Research UK, said: “Research is helping us to find answers to one of cancers’ biggest questions – how tumours develop resistance to many of our most effective drugs.

“New techniques like this blood test, which offers a more personalised approach to treating cancers, will help us improve the effectiveness of treatments for patients.”